Many ribosomal protein genes are cancer genes in zebrafish.

Many ribosomal protein genes are cancer genes in zebrafish.

We have generated several hundred lines of zebrafish (Danio rerio), each heterozygous for a recessive embryonic lethal mutation. Since many tumor suppressor genes are recessive lethals, we screened our colony for lines that display early mortality and/or gross evidence of tumors. We identified 12 li...

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Bibliographic Details
Main Authors: Adam Amsterdam, Kirsten C Sadler, Kevin Lai, Sarah Farrington, Roderick T Bronson, Jacqueline A Lees, Nancy Hopkins
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2004-05-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC406397?pdf=render

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http://europepmc.org/articles/PMC406397?pdf=render

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