Dissociation of DNA damage sensing by endoglycosidase HPSE

Summary: Balance between cell proliferation and elimination is critical in handling threats both exogenous and of internal dysfunction. Recent work has implicated a conserved but poorly understood endoglycosidase heparanase (HPSE) in the restriction of innate defense responses, yet biochemical media...

Full description

Bibliographic Details
Main Authors: Alex Agelidis, Rahul K. Suryawanshi, Chandrashekhar D. Patil, Anaamika Campeau, David J. Gonzalez, Deepak Shukla
Format: Article
Language:English
Published: Elsevier 2021-03-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004221002108