Resting regulatory CD4 T cells: a site of HIV persistence in patients on long-term effective antiretroviral therapy.

Resting regulatory CD4 T cells: a site of HIV persistence in patients on long-term effective antiretroviral therapy.

BACKGROUND: In HIV-infected patients on long-term HAART, virus persistence in resting long-lived CD4 T cells is a major barrier to curing the infection. Cell quiescence, by favouring HIV latency, reduces the risk of recognition and cell destruction by cytotoxic lymphocytes. Several cell-activation-b...

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Bibliographic Details
Main Authors: Tu-Anh Tran, Marie-Ghislaine de Goër de Herve, Houria Hendel-Chavez, Bamory Dembele, Emilie Le Névot, Karim Abbed, Coralie Pallier, Cécile Goujard, Jacques Gasnault, Jean-François Delfraissy, Anne-Marie Balazuc, Yassine Taoufik
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2551739?pdf=render

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http://europepmc.org/articles/PMC2551739?pdf=render

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