The <it>R337H </it>mutation in <it>TP53 </it>and breast cancer in Brazil

<p>Abstract</p> <p>Background</p> <p>Germline mutations in p53 are associated with the Li-Fraumeni Syndrome which is characterized by childhood cancers, including pediatric adrenal cortical carcinomas and early onset breast cancer. The high incidence of adrenal cortical...

Full description

Bibliographic Details
Main Authors: Gomes Magda CB, Kotsopoulos Joanne, de Almeida Gutemberg, Costa Mauricio M, Vieira Roberto, Filho Firmino de AG, Pitombo Marcos B, F Leal Paulo, Royer Robert, Zhang Phil, Narod Steven A
Format: Article
Language:English
Published: BMC 2012-03-01
Series:Hereditary Cancer in Clinical Practice
Subjects:
Online Access:http://www.hccpjournal.com/content/10/1/3