Toxoplasma gondii peptide ligands open the gate of the HLA class I binding groove

Toxoplasma gondii peptide ligands open the gate of the HLA class I binding groove

HLA class I presentation of pathogen-derived peptide ligands is essential for CD8+ T-cell recognition of Toxoplasma gondii infected cells. Currently, little data exist pertaining to peptides that are presented after T. gondii infection. Herein we purify HLA-A*02:01 complexes from T. gondii infected...

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Bibliographic Details
Main Authors: Curtis McMurtrey, Thomas Trolle, Tiffany Sansom, Soumya G Remesh, Thomas Kaever, Wilfried Bardet, Kenneth Jackson, Rima McLeod, Alessandro Sette, Morten Nielsen, Dirk M Zajonc, Ira J Blader, Bjoern Peters, William Hildebrand
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2016-01-01
Series:eLife
Subjects:
T. gondii
HLA
peptide ligands
mass spectrometry
crystallography
Online Access:https://elifesciences.org/articles/12556

Internet

https://elifesciences.org/articles/12556

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