Maturation State-Specific Alternative Splicing in <i>FLT3</i>-ITD and NPM1 Mutated AML

Maturation State-Specific Alternative Splicing in <i>FLT3</i>-ITD and NPM1 Mutated AML

Despite substantial progress achieved in unraveling the genetics of AML in the past decade, its treatment outcome has not substantially improved. Therefore, it is important to better understand how genetic mutations translate to phenotypic features of AML cells to further improve response prediction...

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Bibliographic Details
Main Authors: Anna Wojtuszkiewicz, Inge van der Werf, Stephan Hutter, Wencke Walter, Constance Baer, Wolfgang Kern, Jeroen J. W. M. Janssen, Gert J. Ossenkoppele, Claudia Haferlach, Jacqueline Cloos, Torsten Haferlach
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Cancers
Subjects:
alternative splicing
acute myeloid leukemia
<i>FLT3</i>-ITD
NPM1
FAB
maturation state
Online Access:https://www.mdpi.com/2072-6694/13/16/3929

Internet

https://www.mdpi.com/2072-6694/13/16/3929

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