The mitochondrial COI/tRNASER(UCN) G7444A mutation may be associated with hearing impairment in a Han Chinese family

The mitochondrial COI/tRNASER(UCN) G7444A mutation may be associated with hearing impairment in a Han Chinese family

Variations in mitochondrial genome have been found to be associated with hearing loss. Of these, the mitochondrial 12S rRNA and tRNASer(UCN) are the hot-spots for pathogenic variants associated with deafness. To understand the putative role of mitochondrial DNA (mtDNA) variants in hearing loss, we r...

Full description

Bibliographic Details
Main Authors: Ding Y, Xia B-H, Teng Y-S, Zhuo G-C, Leng J-H
Format: Article
Language:English
Published: Sciendo 2017-12-01
Series:Balkan Journal of Medical Genetics
Subjects:
c1494t
g7444a
chinese family
deafness
mitochondrial dna (mtdna)
pathogenic variants
Online Access:https://doi.org/10.1515/bjmg-2017-0025

Internet

https://doi.org/10.1515/bjmg-2017-0025

Similar Items