Vitamin D/VDR signaling inhibits LPS-induced IFNγ and IL-1β in Oral epithelia by regulating hypoxia-inducible factor-1α signaling pathway

Vitamin D/VDR signaling inhibits LPS-induced IFNγ and IL-1β in Oral epithelia by regulating hypoxia-inducible factor-1α signaling pathway

Abstract Background Oral lichen planus (OLP) is known as a chronic inflammatory disease. Our recent studies have suggested that vitamin D/vitamin D receptor (VDR) signaling exerts its protective effects on oral keratinocyte apoptosis by regulating microRNA-802 and p53-upregulated modulator of apopto...

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Bibliographic Details
Main Authors: Xuejun Ge, Lixiang Wang, Mengdi Li, Na Xu, Feiyan Yu, Fang Yang, Ran Li, Fang Zhang, Bin Zhao, Jie Du
Format: Article
Language:English
Published: BMC 2019-02-01
Series:Cell Communication and Signaling
Subjects:
Vitamin D
Vitamin D receptor
HIF-1α
Cytokines
Oral lichen planus
Online Access:http://link.springer.com/article/10.1186/s12964-019-0331-9

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http://link.springer.com/article/10.1186/s12964-019-0331-9

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