Bone Marrow-Derived VSELs Engraft as Lung Epithelial Progenitor Cells after Bleomycin-Induced Lung Injury

Bone Marrow-Derived VSELs Engraft as Lung Epithelial Progenitor Cells after Bleomycin-Induced Lung Injury

Background: Alveolar type 2 (AT2) cells and bronchioalveolar stem cells (BASC) perform critical regenerative functions in response to lung damage. Published data show that nonhematopoietic, bone marrow-derived “very small embryonic-like stem cells” (VSELs) can differentiate in vivo into surfactant p...

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Bibliographic Details
Main Authors: Andrzej K. Ciechanowicz, Katarzyna Sielatycka, Monika Cymer, Marta Skoda, Malwina Suszyńska, Kamila Bujko, Mariusz Z. Ratajczak, Diane S. Krause, Magdalena Kucia
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Cells
Subjects:
alveolar type II cells
bronchioalveolar stem cells
very small embryonic-like stem cells
regenerative medicine
bleomycin-induced injury
lung regeneration
Online Access:https://www.mdpi.com/2073-4409/10/7/1570

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https://www.mdpi.com/2073-4409/10/7/1570

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