Reliable LC3 and p62 autophagy marker detection in formalin fixed paraffin embedded human tissue by immunohistochemistry

Autophagy assures cellular homeostasis, and gains increasing importance in cancer, where it impacts on carcinogenesis, propagation of the malignant phenotype and development of resistance. To date, its tissue-based analysis by immunohistochemistry remains poorly standardized. Here we show the feasib...

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Bibliographic Details
Main Authors: A.M. Schläfli, S. Berezowska, O. Adams, R. Langer, M.P. Tschan
Format: Article
Language:English
Published: PAGEPress Publications 2015-05-01
Series:European Journal of Histochemistry
Subjects:
p62
Online Access:http://ejh.it/index.php/ejh/article/view/2481