Evaluation of whole-genome DNA methylation sequencing library preparation protocols

Evaluation of whole-genome DNA methylation sequencing library preparation protocols

Abstract Background With rapidly dropping sequencing cost, the popularity of whole-genome DNA methylation sequencing has been on the rise. Multiple library preparation protocols currently exist. We have performed 22 whole-genome DNA methylation sequencing experiments on snap frozen human samples, an...

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Bibliographic Details
Main Authors: Jacob Morrison, Julie M. Koeman, Benjamin K. Johnson, Kelly K. Foy, Ian Beddows, Wanding Zhou, David W. Chesla, Larissa L. Rossell, Emily J. Siegwald, Marie Adams, Hui Shen
Format: Article
Language:English
Published: BMC 2021-06-01
Series:Epigenetics & Chromatin
Subjects:
DNA methylation
Epigenetics
Whole-genome bisulfite sequencing
Enzymatic methylation sequencing
Fallopian tube
Online Access:https://doi.org/10.1186/s13072-021-00401-y

Internet

https://doi.org/10.1186/s13072-021-00401-y

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