Abundance and size of hyaluronan in naked mole-rat tissues and plasma

Abstract Large amounts of ultra-high molecular weight hyaluronan (HA) have been described as the main cause of cancer resistance in naked mole-rats (Heterocephalus glaber, NMR). Our work examined HA metabolism in these rodents more closely. HA was localized and quantified using HA binding proteins....

Full description

Bibliographic Details
Main Authors: Delphine del Marmol, Susanne Holtze, Nadia Kichler, Arne Sahm, Benoit Bihin, Virginie Bourguignon, Sophie Dogné, Karol Szafranski, Thomas Bernd Hildebrandt, Bruno Flamion
Format: Article
Language:English
Published: Nature Publishing Group 2021-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-86967-9