Identification of Genetic Alterations, as Causative Genetic Defects in Long QT Syndrome, Using Next Generation Sequencing Technology.

Identification of Genetic Alterations, as Causative Genetic Defects in Long QT Syndrome, Using Next Generation Sequencing Technology.

BACKGROUND:Long QT Syndrome is an inherited channelopathy leading to sudden cardiac death due to ventricular arrhythmias. Despite that several genes have been associated with the disease, nearly 20% of cases remain without an identified genetic cause. Other genetic alterations such as copy number va...

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Bibliographic Details
Main Authors: Oscar Campuzano, Georgia Sarquella-Brugada, Irene Mademont-Soler, Catarina Allegue, Sergi Cesar, Carles Ferrer-Costa, Monica Coll, Jesus Mates, Anna Iglesias, Josep Brugada, Ramon Brugada
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4262446?pdf=render

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http://europepmc.org/articles/PMC4262446?pdf=render

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