Targeted next-generation sequencing to diagnose disorders of HDL cholesterol

Targeted next-generation sequencing to diagnose disorders of HDL cholesterol

A low level of HDL cholesterol (HDL-C) is a common clinical scenario and an important marker for increased cardiovascular risk. Many patients with very low or very high HDL-C have a rare mutation in one of several genes, but identification of the molecular abnormality in patients with extreme HDL-C...

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Bibliographic Details
Main Authors: Singh N. Sadananda, Jia Nee Foo, Meng Tiak Toh, Lubomira Cermakova, Laia Trigueros-Motos, Teddy Chan, Herty Liany, Jennifer A. Collins, Sima Gerami, Roshni R. Singaraja, Michael R. Hayden, Gordon A. Francis, Jiri Frohlich, Chiea Chuen Khor, Liam R. Brunham
Format: Article
Language:English
Published: Elsevier 2015-10-01
Series:Journal of Lipid Research
Subjects:
ATP binding cassette transporter A1
diagnostic tools
genetics
genomics
high density lipoprotein
atherosclerosis
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520309743

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http://www.sciencedirect.com/science/article/pii/S0022227520309743

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