cGMP-dependent protein kinase I is crucial for angiogenesis and postnatal vasculogenesis.

BACKGROUND: Endothelium-derived nitric oxide plays an important role for the bone marrow microenvironment. Since several important effects of nitric oxide are mediated by cGMP-dependent pathways, we investigated the role of the cGMP downstream effector cGMP-dependent protein kinase I (cGKI) on postn...

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Bibliographic Details
Main Authors: Alexandra Aicher, Christopher Heeschen, Susanne Feil, Franz Hofmann, Michael E Mendelsohn, Robert Feil, Stefanie Dimmeler
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2654072?pdf=render