Maternal-placental-fetal biodistribution of multimodal polymeric nanoparticles in a pregnant rat model in mid and late gestation

Abstract Multimodal polymeric nanoparticles have many exciting diagnostic and therapeutic applications, yet their uptake and passage by the placenta, and applications in the treatment of pregnancy complications have not been thoroughly investigated. In this work, the maternal-fetal-placental biodist...

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Bibliographic Details
Main Authors: Diwei Ho, Joan W. Leong, Rachael C. Crew, Marck Norret, Michael J. House, Peter J. Mark, Brendan J. Waddell, K. Swaminathan Iyer, Jeffrey A. Keelan
Format: Article
Language:English
Published: Nature Publishing Group 2017-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-03128-7