Lower Locus Coeruleus MRI intensity in patients with late-life major depression

Lower Locus Coeruleus MRI intensity in patients with late-life major depression

Background The locus coeruleus (LC) is the major noradrenergic source in the central nervous system. Structural alterations in the LC contribute to the pathophysiology of different neuropsychiatric disorders, which may increase to a variable extent the likelihood of developing neurodegenerative cond...

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Bibliographic Details
Main Authors: Andrés Guinea-Izquierdo, Mónica Giménez, Ignacio Martínez-Zalacaín, Inés del Cerro, Pol Canal-Noguer, Gerard Blasco, Jordi Gascón, Ramon Reñé, Inmaculada Rico, Angels Camins, Carlos Aguilera, Mikel Urretavizcaya, Isidre Ferrer, José Manuel Menchón, Virginia Soria, Carles Soriano-Mas
Format: Article
Language:English
Published: PeerJ Inc. 2021-02-01
Series:PeerJ
Subjects:
Major depressive disorder
Amnestic mild cognitive impairment
Locus coeruleus
Magnetic resonance imaging
Neuromelanin
Serotonin/norepinephrine reuptake inhibitors
Online Access:https://peerj.com/articles/10828.pdf

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https://peerj.com/articles/10828.pdf

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