Computational detection of stage-specific transcription factor clusters during heart development

Computational detection of stage-specific transcription factor clusters during heart development

Transcription factors (TFs) regulate gene expression in living organisms. In higher organisms, TFs often interact in non-random combinations with each other to control gene transcription. Understanding the interactions is key to decipher mechanisms underlying tissue development. The aim of this stud...

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Bibliographic Details
Main Authors: Sebastian eZeidler, Cornelia eMeckbach, Rebecca eTacke, Farah S. eRaad, Angelica eRoa, Shizuka eUchida, Wolfram Hubertus eZimmermann, Edgar eWingender, Mehmet eGültas
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-03-01
Series:Frontiers in Genetics
Subjects:
cardiomyogenesis
Markov clustering
MatrixCatch
TF interaction
Engineered heart muscle
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2016.00033/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fgene.2016.00033/full

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