Pulmonary Toxicity after Total Body Irradiation—An Underrated Complication? Estimation of Risk via Normal Tissue Complication Probability Calculations and Correlation with Clinical Data

Pulmonary Toxicity after Total Body Irradiation—An Underrated Complication? Estimation of Risk via Normal Tissue Complication Probability Calculations and Correlation with Clinical Data

Total body irradiation (TBI) is an essential part of various conditioning regimens prior to allogeneic stem cell transplantation, but is accompanied by relevant (long-term) toxicities. In the lungs, a complex mechanism induces initial inflammation (pneumonitis) followed by chronic fibrosis. The here...

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Bibliographic Details
Main Authors: Michael Oertel, Christopher Kittel, Jonas Martel, Jan-Henrik Mikesch, Marco Glashoerster, Matthias Stelljes, Hans Theodor Eich
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Cancers
Subjects:
total body irradiation
stem cell transplantation
lung toxicity
survivorship
Online Access:https://www.mdpi.com/2072-6694/13/12/2946

Internet

https://www.mdpi.com/2072-6694/13/12/2946

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