miR-124 promotes proliferation and differentiation of neuronal stem cells through inactivating Notch pathway

Abstract Background Neural stem cells (NSCs) are able to differentiate into neurons and astroglia. miRNAs have been demonstrated to be involved in NSC self-renewal, proliferation and differentiation. However, the exact role of miR-124 in the development of NSCs and its underlying mechanism remain to...

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Bibliographic Details
Main Authors: Shujie Jiao, Yaling Liu, Yaobing Yao, Junfang Teng
Format: Article
Language:English
Published: BMC 2017-12-01
Series:Cell & Bioscience
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13578-017-0194-y