Melatonin Improves In Vitro Development of Vitrified-Warmed Mouse Germinal Vesicle Oocytes Potentially via Modulation of Spindle Assembly Checkpoint-Related Genes

Melatonin Improves In Vitro Development of Vitrified-Warmed Mouse Germinal Vesicle Oocytes Potentially via Modulation of Spindle Assembly Checkpoint-Related Genes

The present study aimed to investigate the effect of melatonin (MT) supplementation on in vitro maturation of vitrified mouse germinal vesicle (GV) oocytes. The fresh oocytes were randomly divided into three groups: untreated (control), or vitrified by open-pulled straw method without (vitrification...

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Bibliographic Details
Main Authors: Zhenzheng Wu, Bo Pan, Izhar Hyder Qazi, Haoxuan Yang, Shichao Guo, Jingyu Yang, Yan Zhang, Changjun Zeng, Ming Zhang, Hongbing Han, Qingyong Meng, Guangbin Zhou
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:Cells
Subjects:
melatonin
oocyte vitrification
redox homeostasis
mitochondrial membrane potential
ATP content
spindle assembly checkpoint
mouse
Online Access:https://www.mdpi.com/2073-4409/8/9/1009

Internet

https://www.mdpi.com/2073-4409/8/9/1009

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