Molecular mechanism of histone variant H2A.B on stability and assembly of nucleosome and chromatin structures

Molecular mechanism of histone variant H2A.B on stability and assembly of nucleosome and chromatin structures

Abstract Background H2A.B, the most divergent histone variant of H2A, can significantly modulate nucleosome and chromatin structures. However, the related structural details and the underlying mechanism remain elusive to date. In this work, we built atomic models of the H2A.B-containing nucleosome c...

Full description

Bibliographic Details
Main Authors: Junhui Peng, Chuang Yuan, Xinfan Hua, Zhiyong Zhang
Format: Article
Language:English
Published: BMC 2020-07-01
Series:Epigenetics & Chromatin
Subjects:
Histone variant H2A.B
Multiscale modeling
Molecular dynamics
Coarse-grained simulations
Online Access:http://link.springer.com/article/10.1186/s13072-020-00351-x

Internet

http://link.springer.com/article/10.1186/s13072-020-00351-x

Similar Items