Reactive oxygen species derived from NOX3 and NOX5 drive differentiation of human oligodendrocytes

Reactive oxygen species derived from NOX3 and NOX5 drive differentiation of human oligodendrocytes

Reactive oxygen species (ROS) are signaling molecules that mediate stress response, apoptosis, DNA damage, gene expression and differentiation. We report here that differentiation of oligodendrocytes, the myelin forming cells in the CNS, is driven by ROS. To dissect the oligodendrocyte differentiati...

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Bibliographic Details
Main Authors: Roberta eAccetta, Simona eDamiano, Annalisa eMorano, Paolo eMondola, Roberto ePaternò, Enrico Vittorio Avvedimento, Mariarosaria eSantillo
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-06-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Multiple Sclerosis
Reactive Oxygen Species
differentiation
oligodendrocyte
NOX3
NOX5
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2016.00146/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fncel.2016.00146/full

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