High monocyte to lymphocyte ratio is associated with impaired protection after subcutaneous administration of BCG in a mouse model of tuberculosis [version 2; referees: 2 approved]
Background: The only available tuberculosis (TB) vaccine, Bacillus Calmette-Guérin (BCG), has variable efficacy. New vaccines are therefore urgently needed. Why BCG fails is incompletely understood, and the tools used for early assessment of new vaccine candidates do not account for BCG variability....
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
F1000 Research Ltd
2018-06-01
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Series: | F1000Research |
Online Access: | https://f1000research.com/articles/7-296/v2 |