Microsyntenic Clusters Reveal Conservation of lncRNAs in Chordates Despite Absence of Sequence Conservation

Microsyntenic Clusters Reveal Conservation of lncRNAs in Chordates Despite Absence of Sequence Conservation

Homologous long non-coding RNAs (lncRNAs) are elusive to identify by sequence similarity due to their fast-evolutionary rate. Here we develop LincOFinder, a pipeline that finds conserved intergenic lncRNAs (lincRNAs) between distant related species by means of microsynteny analyses. Using this tool,...

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Bibliographic Details
Main Authors: Carlos Herrera-Úbeda, Marta Marín-Barba, Enrique Navas-Pérez, Jan Gravemeyer, Beatriz Albuixech-Crespo, Grant N. Wheeler, Jordi Garcia-Fernàndez
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:Biology
Subjects:
lncRNAs
genome_evolution
synteny
amphioxus
Online Access:https://www.mdpi.com/2079-7737/8/3/61

Internet

https://www.mdpi.com/2079-7737/8/3/61

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