The matching quality of experimental and control interventions in blinded pharmacological randomised clinical trials: a methodological systematic review
Abstract Background Blinding is a pivotal method to avoid bias in randomised clinical trials. In blinded drug trials, experimental and control interventions are often designed to be matched, i.e. to appear indistinguishable. It is unknown how often matching procedures are inadequate, so we decided t...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2016-02-01
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Series: | BMC Medical Research Methodology |
Online Access: | http://link.springer.com/article/10.1186/s12874-016-0111-9 |