Optimized Structure-based Methodology for Studying PPARγ Partial Agonists
The peroxisome proliferator-activated receptor (PPAR) γ is a master regulator of the lipid and glucose metabolism, and thus is a valuable drug target. Since its full activation is accompanied by a number of adverse effects, researchers focus on discovery of novel compounds with ligand-receptor inter...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Bulgarian Academy of Sciences
2018-03-01
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Series: | International Journal Bioautomation |
Subjects: | |
Online Access: | http://www.biomed.bas.bg/bioautomation/2018/vol_22.1/files/22.1_07.pdf |