Hearing Loss in Id1−/−; Id3+/− and Id1+/−; Id3−/− Mice Is Associated With a High Incidence of Middle Ear Infection (Otitis Media)

Hearing Loss in Id1−/−; Id3+/− and Id1+/−; Id3−/− Mice Is Associated With a High Incidence of Middle Ear Infection (Otitis Media)

Inhibitors of differentiation/DNA binding (Id) proteins are crucial for inner ear development, but whether Id mutations affect middle ear function remains unknown. In this study, we obtained Id1−/−; Id3+/− mice and Id1+/−; Id3−/− mice and carefully examined their middle ear morphology and auditory f...

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Bibliographic Details
Main Authors: Qingyin Zheng, Tihua Zheng, Aizhen Zhang, Bin Yan, Bo Li, Zhaoqiang Zhang, Yan Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Genetics
Subjects:
otitis media
mouse model
hearing loss
inflammation
genetic predisposition
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2021.508750/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2021.508750/full

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