Prolonged Morphine Exposure Induces Increased Firm Adhesion in an in Vitro Model of the Blood–Brain Barrier

Prolonged Morphine Exposure Induces Increased Firm Adhesion in an in Vitro Model of the Blood–Brain Barrier

The blood–brain barrier (BBB) has been defined as a critically important protective barrier that is involved in providing essential biologic, physiologic, and immunologic separation between the central nervous system (CNS) and the periphery. Insults to the BBB can cause overall barrier damage or der...

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Bibliographic Details
Main Authors: Marianne Strazza, Vanessa Pirrone, Brian Wigdahl, Will Dampier, Wei Lin, Rui Feng, Monique E. Maubert, Babette Weksler, Ignacio A. Romero, Pierre-Olivier Couraud, Michael R. Nonnemacher
Format: Article
Language:English
Published: MDPI AG 2016-06-01
Series:International Journal of Molecular Sciences
Subjects:
blood–brain barrier
brain microvascular endothelial cells (BMEC)
morphine
(peripheral blood mononuclear cell) PBMC
cellular adhesion molecules (CAM)
Online Access:http://www.mdpi.com/1422-0067/17/6/916

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http://www.mdpi.com/1422-0067/17/6/916

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