Polymorphisms in Pvkelch12 and gene amplification of Pvplasmepsin4 in Plasmodium vivax from Thailand, Lao PDR and Cambodia

Polymorphisms in Pvkelch12 and gene amplification of Pvplasmepsin4 in Plasmodium vivax from Thailand, Lao PDR and Cambodia

Abstract Background Mutations in Pfkelch13 and Pfplasmepsin2/3 gene amplification are well-established markers for artemisinin and piperaquine resistance in Plasmodium falciparum, a widespread problem in the Greater Mekong Subregion (GMS). The Plasmodium vivax parasite population has experienced var...

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Bibliographic Details
Main Authors: Jureeporn Duanguppama, Vivek Bhakta Mathema, Rupam Tripura, Nicholas P. J. Day, Mayfong Maxay, Chea Nguon, Lorenz von Seidlein, Mehul Dhorda, Thomas J. Peto, Francois Nosten, Nicholas J. White, Arjen M. Dondorp, Mallika Imwong
Format: Article
Language:English
Published: BMC 2019-04-01
Series:Malaria Journal
Subjects:
Drug pressure
SNPs
P. vivax
CNV
Malaria
Mutations
Online Access:http://link.springer.com/article/10.1186/s12936-019-2749-3

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http://link.springer.com/article/10.1186/s12936-019-2749-3

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