Inhibition of DDR1 reduces invasive features of human A375 melanoma, HT29 colon carcinoma and SK-HEP hepatoma cells

Inhibition of DDR1 reduces invasive features of human A375 melanoma, HT29 colon carcinoma and SK-HEP hepatoma cells

DDR1 is a receptor tyrosine kinases for collagen and an adverse prognostic factor in primary and metastatic tumors.Despite this, DDR1 signaling and its functional consequences in tumor development remain unclear. RT-PCR and Western blot show that A375, colon carcinoma HT29 and liver carcinoma SK-HEP...

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Bibliographic Details
Main Authors: Irene Romayor, Iker Badiola, Elvira Olaso
Format: Article
Language:English
Published: Taylor & Francis Group 2020-01-01
Series:Cell Adhesion & Migration
Subjects:
melanoma
colon carcinoma
hepatocarcinoma
discoidin domain receptor 1
matrix metalloproteinases
collagen receptor
silencing
adhesion
proliferation
migration
invasion
Online Access:http://dx.doi.org/10.1080/19336918.2020.1733892

Internet

http://dx.doi.org/10.1080/19336918.2020.1733892

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