Propofol-induced changes in neurotrophic signaling in the developing nervous system in vivo.

Several studies have revealed a role for neurotrophins in anesthesia-induced neurotoxicity in the developing brain. In this study we monitored the spatial and temporal expression of neurotrophic signaling molecules in the brain of 14-day-old (PND14) Wistar rats after the application of a single prop...

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Bibliographic Details
Main Authors: Jelena Popic, Vesna Pesic, Desanka Milanovic, Smilja Todorovic, Selma Kanazir, Vesna Jevtovic-Todorovic, Sabera Ruzdijic
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3319585?pdf=render