Amino Acid Starvation Sensitizes Resistant Breast Cancer to Doxorubicin-Induced Cell Death

Many clinical trials are beginning to assess the effectiveness of compounds known to regulate autophagy in patients receiving anti-cancer chemotherapy. However, autophagy inhibition, through exogenous inhibitors, or activation, through starvation, has revealed conflicting roles in cancer management...

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Bibliographic Details
Main Authors: Mark Thomas, Tanja Davis, Theo Nell, Balindiwe Sishi, Anna-Mart Engelbrecht
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2020.565915/full