Noninvasive assessment of gene transfer and expression by in vivo functional and morphologic imaging in a rabbit tumor model.

Noninvasive assessment of gene transfer and expression by in vivo functional and morphologic imaging in a rabbit tumor model.

To evaluate the importance of morphology in quantifying expression after in vivo gene transfer and to compare gene expression after intra-arterial (IA) and intra-tumoral (IT) delivery of adenovirus expressing a SSTR2-based reporter gene in a large animal tumor model.Tumor directed IA or IT delivery...

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Bibliographic Details
Main Authors: Murali K Ravoori, Lin Han, Sheela P Singh, Katherine Dixon, Jyoti Duggal, Ping Liu, Rajesh Uthamanthil, Sanjay Gupta, Kenneth C Wright, Vikas Kundra
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3677885?pdf=render

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http://europepmc.org/articles/PMC3677885?pdf=render

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