Paracrine effects of human amniotic epithelial cells protect against chemotherapy-induced ovarian damage

Paracrine effects of human amniotic epithelial cells protect against chemotherapy-induced ovarian damage

Abstract Background Human amniotic epithelial cells (hAECs) are attractive candidates for regenerative medical therapy, with the potential to replace deficient cells and improve functional recovery after injury. Previous studies have demonstrated that transplantation of hAECs effectively alleviate c...

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Bibliographic Details
Main Authors: Qiuwan Zhang, Shixia Bu, Junyan Sun, Minhua Xu, Xiaofen Yao, Kunyan He, Dongmei Lai
Format: Article
Language:English
Published: BMC 2017-11-01
Series:Stem Cell Research & Therapy
Subjects:
Human amniotic epithelial cells (hAECs)
hAEC-conditioned medium (hAEC-CM)
Premature ovarian failure/insufficiency (POF/POI)
Human granulosa-lutein (hGL) cells
TGF-β
Smad pathway
Online Access:http://link.springer.com/article/10.1186/s13287-017-0721-0

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http://link.springer.com/article/10.1186/s13287-017-0721-0

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