MiR-338-5p promotes metastasis of colorectal cancer by inhibition of phosphatidylinositol 3-kinase, catalytic subunit type 3-mediated autophagy pathwayResearch in context

MiR-338-5p promotes metastasis of colorectal cancer by inhibition of phosphatidylinositol 3-kinase, catalytic subunit type 3-mediated autophagy pathwayResearch in context

Background: In our preliminary screening, expression of miR-338-5p was found to be higher in primary colorectal cancer (CRC) with metastasis. The autophagy related gene- phosphatidylinositol 3-kinase, catalytic subunit type 3 (PIK3C3) appeared to be targeted by miR-338-5p. Here, we provide solid evi...

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Bibliographic Details
Main Authors: Chien-An Chu, Chung-Ta Lee, Jenq-Chang Lee, Yi-Wen Wang, Ching-Tang Huang, Sheng-Hui Lan, Peng-Chan Lin, Bo-Wen Lin, Yu-Feng Tian, Hsiao-Sheng Liu, Nan-Haw Chow
Format: Article
Language:English
Published: Elsevier 2019-05-01
Series:EBioMedicine
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396419302440

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http://www.sciencedirect.com/science/article/pii/S2352396419302440

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