Autophagy mediates serum starvation-induced quiescence in nucleus pulposus stem cells by the regulation of P27

Autophagy mediates serum starvation-induced quiescence in nucleus pulposus stem cells by the regulation of P27

Abstract Background Adult stem cells exist in a quiescent state (G0) within the in vivo niche; the loss of quiescence often leads to a decrease in the number and function of adult stem cells, impairing tissue regeneration and repair. Endogenous repair by nucleus pulposus-derived stem cells has recen...

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Bibliographic Details
Main Authors: Bin Li, Chao Sun, Jing Sun, Ming-hui Yang, Rui Zuo, Chang Liu, Wei-ren Lan, Ming-han Liu, Bo Huang, Yue Zhou
Format: Article
Language:English
Published: BMC 2019-04-01
Series:Stem Cell Research & Therapy
Subjects:
Autophagy
Quiescence
Nucleus pulposus stem cell
P27
Online Access:http://link.springer.com/article/10.1186/s13287-019-1219-8

Internet

http://link.springer.com/article/10.1186/s13287-019-1219-8

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