Entanglement of UPRER in Aging Driven Neurodegenerative Diseases

The endoplasmic reticulum (ER) is an indispensable cellular organelle that remains highly active in neuronal cells. The ER bears the load of maintaining protein homeostasis in the cellular network by managing the folding of incoming nascent peptides; however, the stress imposed by physiological/envi...

Full description

Bibliographic Details
Main Authors: Safikur Rahman, Arif Tasleem Jan, Archana Ayyagari, Jiwoo Kim, Jihoe Kim, Rinki Minakshi
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-10-01
Series:Frontiers in Aging Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fnagi.2017.00341/full