Shared PPARα/γ Target Genes Regulate Brown Adipocyte Thermogenic Function

Shared PPARα/γ Target Genes Regulate Brown Adipocyte Thermogenic Function

Summary: Brown adipose tissue (BAT) generates heat to maintain body temperature and suppress obesity. Agonists for nuclear receptors PPARα and PPARγ both affect brown adipocyte function, yet the interplay between these factors in BAT is uncertain. Here, we report that PPARα shares most genomic bindi...

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Bibliographic Details
Main Authors: Yachen Shen, Yvonne Su, Francisco J. Silva, Angela H. Weller, Jaimarie Sostre-Colón, Paul M. Titchenell, David J. Steger, Patrick Seale, Raymond E. Soccio
Format: Article
Language:English
Published: Elsevier 2020-03-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124720301935

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http://www.sciencedirect.com/science/article/pii/S2211124720301935

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