Genome-wide contribution of genotype by environment interaction to variation of diabetes-related traits.

While genome-wide association studies (GWAS) and candidate gene approaches have identified many genetic variants that contribute to disease risk as main effects, the impact of genotype by environment (GxE) interactions remains rather under-surveyed. To explore the importance of GxE interactions for...

Full description

Bibliographic Details
Main Authors: Ju-Sheng Zheng, Donna K Arnett, Yu-Chi Lee, Jian Shen, Laurence D Parnell, Caren E Smith, Kris Richardson, Duo Li, Ingrid B Borecki, José M Ordovás, Chao-Qiang Lai
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3810463?pdf=render