Genomic Analysis of Salmonella enterica Serovar Typhimurium Characterizes Strain Diversity for Recent U.S. Salmonellosis Cases and Identifies Mutations Linked to Loss of Fitness under Nitrosative and Oxidative Stress

Salmonella enterica serovar Typhimurium is one of the most common S. enterica serovars associated with U.S. foodborne outbreaks. S. Typhimurium bacteria isolated from humans exhibit wide-ranging virulence phenotypes in inbred mice, leading to speculation that some strains are more virulent in nature...

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Main Authors: Hillary S. Hayden, Susana Matamouros, Kyle R. Hager, Mitchell J. Brittnacher, Laurence Rohmer, Matthew C. Radey, Eli J. Weiss, Katie B. Kim, Michael A. Jacobs, Elizabeth H. Sims-Day, Min Yue, Mussaret B. Zaidi, Dieter M. Schifferli, Shannon D. Manning, Judd L. Walson, Samuel I. Miller
Format: Article
Language:English
Published: American Society for Microbiology 2016-03-01
Series:mBio
Online Access:http://mbio.asm.org/cgi/content/full/7/2/e00154-16