Mitochondrial copper and phosphate transporter specificity was defined early in the evolution of eukaryotes

Mitochondrial copper and phosphate transporter specificity was defined early in the evolution of eukaryotes

The mitochondrial carrier family protein SLC25A3 transports both copper and phosphate in mammals, yet in Saccharomyces cerevisiae the transport of these substrates is partitioned across two paralogs: PIC2 and MIR1. To understand the ancestral state of copper and phosphate transport in mitochondria,...

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Bibliographic Details
Main Authors: Xinyu Zhu, Aren Boulet, Katherine M Buckley, Casey B Phillips, Micah G Gammon, Laura E Oldfather, Stanley A Moore, Scot C Leary, Paul A Cobine
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-02-01
Series:eLife
Subjects:
mitochondrial carrier family
copper
phosphate
gene duplications
evolution
mitochondria
Online Access:https://elifesciences.org/articles/64690

Internet

https://elifesciences.org/articles/64690

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