Long-term immunogenicity studies of formalin-inactivated enterovirus 71 whole-virion vaccine in macaques.

Enterovirus 71 (EV71) has caused epidemics of hand, foot and mouth diseases in Asia during the past decades and no vaccine is available. A formalin-inactivated EV71 candidate vaccine (EV71vac) based on B4 subgenotype has previously been developed and found to elicit strong neutralizing antibody resp...

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Bibliographic Details
Main Authors: Chia-Chyi Liu, Chyi-Sing Hwang, Wun-Syue Yang, Dan-Chin Tsai, Sze-Hsien Wu, Ai-Hsiang Chou, Yen-Hung Chow, Suh-Chin Wu, Jen-Ren Wang, Jen-Ron Chiang, Chin-Cheng Huang, Chien-Hsiung Pan, Pele Chong
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4157806?pdf=render