Calycosin-loaded nanoliposomes as potential nanoplatforms for treatment of diabetic nephropathy through regulation of mitochondrial respiratory function

Calycosin-loaded nanoliposomes as potential nanoplatforms for treatment of diabetic nephropathy through regulation of mitochondrial respiratory function

Abstract Backgrounds One of the most common complications in diabetic nephropathy is generation of high levels of ROS which can be regulated by herbal antioxidants. However, polyphenols like calycosin, the bioactive compound of Radix astragali suffer from low solubility and poor bioavailability. Met...

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Bibliographic Details
Main Authors: Chunrong Huang, Lian-Fang Xue, Bo Hu, Huan-Huan Liu, Si-Bo Huang, Suliman Khan, Yu Meng
Format: Article
Language:English
Published: BMC 2021-06-01
Series:Journal of Nanobiotechnology
Subjects:
Diabetic nephropathy
ROS
Calycosin
Nanoliposome
Mitochondria
Online Access:https://doi.org/10.1186/s12951-021-00917-1

Internet

https://doi.org/10.1186/s12951-021-00917-1

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