Telomerase reverse transcriptase mediated immortalization of human bone marrow stromal cells

Primary human bone marrow stromal cells (hMSCs) were transfected with human telomerase reverse transcriptase (hTERT) gene with lipofection method. The hTERT transfected hMSCs of passage 100 underwent chondrogenesis induction with dexamethasone, transforming the growth factor β and vitamin C, osteoge...

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Bibliographic Details
Main Authors: Yong Teng, YunYu Hu, Xu Sheng Li, Zhen Wang, Rui Wang
Format: Article
Language:English
Published: Instituto de Tecnologia do Paraná (Tecpar) 2014-02-01
Series:Brazilian Archives of Biology and Technology
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132014000100006&lng=en&tlng=en