An Ultradian Feeding Schedule in Rats Affects Metabolic Gene Expression in Liver, Brown Adipose Tissue and Skeletal Muscle with Only Mild Effects on Circadian Clocks

An Ultradian Feeding Schedule in Rats Affects Metabolic Gene Expression in Liver, Brown Adipose Tissue and Skeletal Muscle with Only Mild Effects on Circadian Clocks

Restricted feeding is well known to affect expression profiles of both clock and metabolic genes. However, it is unknown whether these changes in metabolic gene expression result from changes in the molecular clock or in feeding behavior. Here we eliminated the daily rhythm in feeding behavior by pr...

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Bibliographic Details
Main Authors: Paul de Goede, Satish Sen, Yan Su, Ewout Foppen, Vincent-Joseph Poirel, Etienne Challet, Andries Kalsbeek
Format: Article
Language:English
Published: MDPI AG 2018-10-01
Series:International Journal of Molecular Sciences
Subjects:
suprachiasmatic nucleus (SCN)
circadian clock
soleus muscle (SM)
brown adipose tissue (BAT)
liver
6-meal feeding
respiratory exchange ratio (RER)
clock genes
metabolic genes
shift work
Online Access:http://www.mdpi.com/1422-0067/19/10/3171

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http://www.mdpi.com/1422-0067/19/10/3171

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