Hepatitis B virus inhibition in mice by lentiviral vector mediated short hairpin RNA

<p>Abstract</p> <p>Background</p> <p>Chronic hepatitis B virus (HBV) infection is an important cause of cirrhosis and hepatocellular carcinoma. The major challenges for current therapies are the low efficacy of current drugs and the occurrence of drug resistant HBV muta...

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Bibliographic Details
Main Authors: Wang Xuehao, You Wei, Gao Yun, Yin Aihong, Xi Lisen, Li Guoqiang, Deng Lei, Sun Beicheng
Format: Article
Language:English
Published: BMC 2009-10-01
Series:BMC Gastroenterology
Online Access:http://www.biomedcentral.com/1471-230X/9/73