Establishment and characterization of patient-derived xenografts as paraclinical models for head and neck cancer

Establishment and characterization of patient-derived xenografts as paraclinical models for head and neck cancer

Abstract Background We investigated whether head and neck squamous cell carcinoma (HNSCC) patient-derived xenografts (PDXs) reaffirm patient responses to anti-cancer therapeutics. Methods Tumors from HNSCC patients were transplanted into immunodeficient mice and propagated via subsequent implantatio...

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Main Authors: Han Na Kang, Jae-Hwan Kim, A-Young Park, Jae Woo Choi, Sun Min Lim, Jinna Kim, Eun Joo Shin, Min Hee Hong, Kyoung-Ho Pyo, Mi Ran Yun, Dong Hwi Kim, Hanna Lee, Sun Och Yoon, Da Hee Kim, Young Min Park, Hyung Kwon Byeon, Inkyung Jung, Soonmyung Paik, Yoon Woo Koh, Byoung Chul Cho, Hye Ryun Kim
Format: Article
Language:English
Published: BMC 2020-04-01
Series:BMC Cancer
Subjects:
Patient-derived xenograft
Biomarker
Head and neck cancer
Squamous cell cancer
Online Access:http://link.springer.com/article/10.1186/s12885-020-06786-5

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http://link.springer.com/article/10.1186/s12885-020-06786-5

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