Experimental chemotherapy for Chagas disease: 15 years of research contributions from in vivo and in vitro studies

Experimental chemotherapy for Chagas disease: 15 years of research contributions from in vivo and in vitro studies

Chagas disease, which is caused by the intracellular parasite Trypanosoma cruzi, is a neglected illness with 12-14 million reported cases in endemic geographic regions of Latin America. While the disease still represents an important public health problem in these affected areas, the available thera...

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Main Authors: Maria de Nazaré C Soeiro, Andréia P Dantas, Anissa Daliry, Cristiane F da Silva, Denise GJ Batista, Elen M de Souza, Gabriel M Oliveira, Kelly Salomão, Marcos Meuser Batista, Michelle GO Pacheco, Patrícia Bernardino da Silva, Ricardo M Santa-Rita, Rubem FS Menna Barreto, David W Boykin, Solange Lisboa de Castro
Format: Article
Language:English
Published: Instituto Oswaldo Cruz, Ministério da Saúde 2009-07-01
Series:Memórias do Instituto Oswaldo Cruz.
Subjects:
Trypanosoma cruzi
Chagas disease
experimental chemotherapy
aromatic diamidines
propolis
N,N-dimethyl-propenamines
naphthoquinones
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762009000900040

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762009000900040

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