Prognostic Interactions between FAP+ Fibroblasts and CD8a+ T Cells in Colon Cancer

Prognostic Interactions between FAP+ Fibroblasts and CD8a+ T Cells in Colon Cancer

Inter-case variations in immune cell and fibroblast composition are associated with prognosis in solid tumors, including colon cancer. A series of experimental studies suggest immune-modulatory roles of marker-defined fibroblast populations, including FAP-positive fibroblasts. These studies imply th...

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Bibliographic Details
Main Authors: Mercedes Herrera, Artur Mezheyeuski, Lisa Villabona, Sara Corvigno, Carina Strell, Christian Klein, Gabriele Hölzlwimmer, Bengt Glimelius, Giuseppe Masucci, Tobias Sjöblom, Arne Östman
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Cancers
Subjects:
colon cancer
tumor microenvironment
cancer associated fibroblasts
T lymphocytes
prognosis
Online Access:https://www.mdpi.com/2072-6694/12/11/3238

Internet

https://www.mdpi.com/2072-6694/12/11/3238

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